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. 2007 Jan 18;580(Pt 1):103–117. doi: 10.1113/jphysiol.2006.125724

Figure 9. Effect of ω-CgTX and ω-Aga-TK on forskolin (FK)-induced inhibition of EPSCs.

Figure 9

A, time course of the inhibitory effect of FK (10 μm) on the EPSCs. B, FK could still inhibit the EPSCs in the presence of ω-CgTX (3 μm). C, FK had no effect in the presence of ω-Aga-TK (200 nm). Superimposed sample records at the right of A, B and C are the averages of 20 consecutive EPSCs during the indicated periods. D, summarized histograms showing the effect of ω-CgTX and ω-Aga-TK on FK-induced inhibition of EPSCs. The inhibition by FK alone was 35.3 ± 1.31% (n = 4). FK-induced inhibition in the presence of ω-Aga-TK (9.31 ± 2.92%, n = 7) was significantly smaller (*P < 0.05) than that by FK alone, whereas FK-induced inhibition in ω-CgTX (35.2 ± 2.74%, n = 5) was not significantly different (P < 0.05) from that of FK alone.