Figure 3. Intracellular l-Arg-activated currents in inside-out membrane patches excised from cardiac myocytes.

A, outward current recorded at +40 mV by superfusing the patch intracellular side with 10 mm l-Arg. B, V_m dependence of current. Equation (1) (with a positive sign within the exponent) was fitted to the data. Currents follow the whole-cell convention, i.e. positive charges moving from the intracellular to the extracellular side of the patch are shown as a positive shift in current. Patch electrode tip diameter: 7.5 μm. Membrane capacitance: 11.6 pF.