Table 1.
PAR2-AP | PAR2-RP | |||
---|---|---|---|---|
Experiment | V50 (mV) | k | V50 (mV) | k |
IA | ||||
Activation | −22.7 ± 6.8 | 27.9 ± 9.2 | −15.2 ± 4.4 | 21.8 ± 4.9 |
Inactivation | −59.2 ± 1.5 | −12.7 ± 1.3 | −59.6 ± 1.7 | −11.9 ± 1.4 |
IK | ||||
Activation | −4.3 ± 5.2 | 19.8 ± 4.9 | 10.1 ± 5.4 | 26.6 ± 3.8 |
Inactivation | −49.7 ± 2.8 | −18.2 ± 3.6 | −52.1 ± 3.4 | −18.5 ± 4.0 |
TTX-R Nav | ||||
Activation | −43.4 ± 1.2 | 3.8 ± 1.0 | −41.5 ± 1.0 | 3.9 ± 0.8 |
Inactivation | −29.9 ± 1.5 | −5.7 ± 1.3 | −31.3 ± 0.5 | −5.3 ± 0.4 |
PAR2 activation did not alter voltage of half-activation/inactivation (V50) or the slope (k) in IA, IK, or TTX-resistant Na+ currents.