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. 2007 Feb 8;580(Pt 3):977–991. doi: 10.1113/jphysiol.2006.126599

Table 1.

The effect of PAR2 activation on V50 and k-values

PAR2-AP PAR2-RP


Experiment V50 (mV) k V50 (mV) k
IA
 Activation −22.7 ± 6.8 27.9 ± 9.2 −15.2 ± 4.4 21.8 ± 4.9
 Inactivation −59.2 ± 1.5 −12.7 ± 1.3 −59.6 ± 1.7 −11.9 ± 1.4
IK
 Activation −4.3 ± 5.2 19.8 ± 4.9 10.1 ± 5.4 26.6 ± 3.8
 Inactivation −49.7 ± 2.8 −18.2 ± 3.6 −52.1 ± 3.4 −18.5 ± 4.0
TTX-R Nav
 Activation −43.4 ± 1.2 3.8 ± 1.0 −41.5 ± 1.0 3.9 ± 0.8
 Inactivation −29.9 ± 1.5 −5.7 ± 1.3 −31.3 ± 0.5 −5.3 ± 0.4

PAR2 activation did not alter voltage of half-activation/inactivation (V50) or the slope (k) in IA, IK, or TTX-resistant Na+ currents.