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. 2006 Dec 21;580(Pt 2):373–383. doi: 10.1113/jphysiol.2006.123570

Figure 2. The NMDAR-mediated tonic current is not sensitive to increases in the concentration of ambient glycine or D-serine.

Figure 2

A, applications of d-serine (D-Ser, 30 μm) and of the glycine transporter inhibitor sarcosine (Sarco, 500 μm) had no effect on the holding current while the glutamate transporter inhibitor TBOA (100 μm) induced a large tonic current. B, histogram of the effects of d-serine (30, 250, 500 μm), sarcosine (500 μm) and TBOA (100 μm) on the holding current of pyramidal cells.