Table I.
RCTs examining MBP
| Zmora 2003 | Fa-Si-Oen 2005 | Ram 2005 | Bucher 2005 | Miettinen 2000 | |
|---|---|---|---|---|---|
| No. of patients included | 415 | 250 | 329 | 153 | 267 |
| No. of patients excluded | 35 | 0 | Not given | 0 | 12 |
| No. of pt (MBP/no MBP) | 187/193 | 125/125 | 164/165 | 78/75 | 138/129 |
| Mean age (MBP/no MBP) | 68/68 | 68/70 (median) | 68/68 | 63/63 | 61/64 |
| Cancer % (MBP/no MBP) | 78/78 | 90/92 | 75/88 | 32/28 | 46/55 |
| L colon surgery % (MBP/no MBP) | 68/72 | 48/58 | 89/85 | 100/100 | 45/47 |
| Type of prep | Polyethylene glycol | Polyethylene glycol | Sodium phosphate | Polyethylene glycol | Polyethylene glycol |
| Antibiotic | Yes | Yes | Yes | Yes | Yes |
| Same length of prophylaxis | No | Yes | Yes | No | Yes |
| Rectal enema | Yes | No | No | Yes | No |
| Anastomosis % (stapled / handsewn) | Not given | 7/93 (MBP) 8/92 (no MBP) | 94/6 (MBP) 98/2 (no MBP) | Not given | 60/30 (MBP) 62/28 (no MBP) |
| Surgeon/trainee % | Not given | 42/59 (MBP) 50/50 (no MBP) | 37/63 (MBP) 32/68 (no MBP) | Not given | Not given |
| Anastomotic leak % (MBP / no MBP) | 3.7/2.1 (NS) | 5.6/4.8 (NS) | 0.6/1.2 (NS) | 6/1 (NS) | 4/2 (NS) |
| Wound infection % (MBP / no MBP) | 6.4/5.7 (NS) | 7.2/5.6 (NS) | 9.8/6.1 (NS) | 13/4 (NS) | 4/2 (NS) |
| Intra-abdominal abscess % (MBP / no MBP) | 1.1/1 (NS) | Not given | 0.6/0.6 (NS) | 1/3 (NS) | 2/3 (NS) |
NS = not significant