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Comparison of the phenotype of MK5 deficiency with the MK2-deficient inflammatory phenotype. (A) Survival of LPS-galactosamine-induced endotoxic shock. wt, wild type. (B) LPS-induced cytokine (TNF, IL, and IFN) production of spleen cell cultures from MK5- and MK2-deficient mice plotted as percentages of cytokine production of wild-type spleen cells. Results are shown as means ± standard errors of the means (n = 24 in each group).
