TABLE 2.
Effect of mutations associated with endocytosis on toxicity of 103Q
| Genea | Toxicityb |
|---|---|
| abp1 | Same |
| aip1 | - |
| apm4 | Same |
| ark1 | Same |
| apl1 | - |
| apl3 | Same |
| bul1 | Same |
| chc1 | -- |
| clc1 | -- |
| ede1 | - |
| end3 | - |
| end3-1 | - |
| end8-1 | -- |
| end9-1 | -- |
| end10-1 | -- |
| end11 | -- |
| ent1 | Same |
| ent2 | Same |
| mkk2 | Same |
| myo3 | Same |
| pan1 | - |
| pan2 | Same |
| prk1 | Same |
| rex3 | Same |
| rvs161 | - |
| rvs167 | - |
| she4 | - |
| sac6 | Same |
| sjl1 | - |
| sjl2 | Same |
| sjl3 | Same |
| sla1 | - |
| sla2 | - |
| srv2 | -- |
| vid31 | Same |
| vma2 | Same |
| vps11 | - |
| vps13 | - |
| vps15 | Same |
| vps33 | Same |
| vrp1 | - |
Underlining indicates mutant genes; all others are deletions.
Same, toxic effect of 103Q expression is close to that seen with the wild type; -, mutant cells expressing 103Q form much smaller colonies than wild-type cells; --, almost no growth on selective galactose media.