Fig. 5.

Qdots exert no discernable influence on neurotransmission. (A and B) Fluorescence or photoluminescence changes of FM4-64 or Qdot during field stimulation (hatched bar) or high K⁺ challenge (black bar). Data represent three loading conditions, Qdots only (red circles), FM4-64 only (blue triangles), or FM4-64 at Qdot co-loaded boutons (filled black squares). Intensities of photoluminescent/fluorescent signals normalized as in previous figures. (C) Samples of EPSCs recorded before and after Qdot loading or from sham control. Ratio of EPSCs recorded after and before Qdot loading (recovery/baseline). No significant difference between Qdot-loaded and sham control neurons (P > 0.25, t test).