Table 1.
Demographics of cases used for genotyping and expression
| Gender | Age | |||
|---|---|---|---|---|
| Source | Tissue | Diagnosis | (M/F) | Avg (StDev) |
| Genotyping | ||||
| Conte-Pritzker (DNA) | Postmortem-CB | Control (n=20) | 13/7 | 52.6 (16.5) |
| BPD (n=9) | 6/3 | 63.9 (17.7) | ||
| MDD (n=11) | 7/4 | 50.7 (14.8) | ||
| Total (n=40) | 26/14 | 52.6 (16.5) | ||
| NIMH (DNA) | Lymphocyte | BPD (n=26) | 10/16 | 45.5 (9.3) |
| Postmortem-DLPFC | ||||
| Stanley Foundation | Control (n=35) | 26/9 | 42.5 (7.6) | |
| Samples (DNA) | BPD (n=35) | 17/18 | 45.3 (10.5) | |
| SZ (n=35) | 26/9 | 42.6 (8.5) | ||
| Total (n=105) | 69/36 | 44.0 (8.9) | ||
| Expression | ||||
| Conte-Pritzker (cDNA) | Postmortem-DLPFC | Control (n=13) | 11/2 | 48.0 (17.6) |
| BPD (n=8) | 5/3 | 52.0 (17.9) | ||
| MDD (n=10) | 7/3 | 48.5 (13.51) | ||
| Total (n=31) | 23/8 | 49.2 (17.7) | ||
| Genotype Analysis | ||||
| Total Samples | Control (n=55) | 39/16 | 47.6 (12.1) | |
| BPD (n=70) | 33/37 | 51.6 (12.5) | ||
| SZ (n=35) | 26/9 | 42.6 (8.5) | ||
| Total (n=160) | 98/62 | 47.3 (11.0) |
BPD, bipolar disorder; DLPFC, dorsalateral prefrontal cortex; F, female; M, male; MDD, major depressive disorder; NIMH, National Institute of Mental Health; SZ, schizophrenia.