Figure 1.

Antibody levels in the sera of mice immunized with the CDR-based peptides. Sera of individual BALB/c (a and b) or SJL mice (c and d) immunized with either mAb 5G12 (□) or the peptides pCDR1 (∗), pCDR3 (┌), or p278 (▵) taken 3 months after the booster injection, and sera of age matched naive mice (⊞), were tested for anti-single-stranded DNA (a and c) and anti-16/6 Id (b and d) antibody titers. Results are expressed as mean OD ± SD of each mouse group. No significant background binding to uncoated plates (OD ≤ 0.05) could be detected with all sera tested.