Figure 4.

In vivo inhibition of LNC proliferation. BALB/c (a) or SJL (b) mice were immunized i.d. in CFA with pCDR1 or pCDR3, respectively. The mice were also injected (i.p.) with 200 μg of the above immunizing peptides in PBS, either 3 days before immunization (□), at immunization day (○), or at both dates (▵). Mice that were not treated (▪), or treated with a control peptide, p307 (┌) were used as controls. LNC proliferation was then carried out as described. Results are expressed as mean cpm of triplicates. SD values did not exceed 10%.