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Gαi2 in neutrophils is responsible for chemokine-induced neutrophil arrest. Number of adherent leukocytes in cremaster muscle postcapillary venules of Gnai2−/− → Gnai2+/+ chimeric mice and Gnai2+/+ mice after intravenous injection of 600 ng CXCL1 (normalized for blood neutrophil counts). Data were recorded and analyzed for 1 minute starting 15 seconds after CXCL1 injection. Data presented as means plus or minus SEM from at least 4 mice.
