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. Author manuscript; available in PMC: 2008 Sep 1.
Published in final edited form as: J Cyst Fibros. 2007 Feb 27;6(5):351–359. doi: 10.1016/j.jcf.2007.01.001

Figure 1. Apical addition of high dose quinine to Calu-3 monolayers.

Figure 1

Cells were grown at an air-liquid interface and studied in Ussing chambers. A: Calu-3 cells in Ringers solution followed by 1) mucosal (M) low- Cl− solution, 2) addition of 1 mg/mL quinine, and 3) addition of 200 μM glybenclamide. B: Same experiment as in A, with mucosal and serosal low- Cl− solution (i.e. no chloride gradient) prior to addition of quinine.