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. 2006 Jun 5;77(12):1350–1353. doi: 10.1136/jnnp.2004.060731

Table 1 Clinical manifestations.

Number (n = 51) % LB‐IgG positive LB‐IgM positive Systemic features LB LB‐IgM and systemic LB
Meningeal symptoms:
 Headache or Meningism 47 92 30 34 23 17
 CSF pleocytosis 42 95*
 Lymphocytic 26 62†
 Polymorphonuclear 8 19†
 mixed 8 19†
Neurological features:
 Tremor 22 43 15 10 4 4
 Nystagmus 12 24 8 7 2 2
 Muscle weakness 21 41 13 16 11 8
 Flaccid paresis arms and shoulders 14 28 10 11 6 6
 Flaccid paresis legs 8 16 6 7 5 4
 Spastic paresis 6 12 3 5 4 3
 Bulbar or respiratory dysfunction 3 6 2 1 2 1
 Facial palsy 3 6 1 3 1 1
 Oculomotor disturbances 2 4 1 1
 Distal polyneuropathy 4 8 3 2 2 2
 Migrating, radicular, limb pains 21 41 13 16 10 8
Systemic features:
 Biphasic fever 28 55 23 17 12 8
 Early local erythema (>5 cm) 7 14 4 4
 Erythema chronicum migrans 1 2 1 1
 Joint involvement 9 18 6 7
  Arthralgias 7 14 4 5
  Swelling 2 4 2 2
 Atrio‐ventricular block 5 10 5 3
  His Bundle block 10 20 5 8
Seropositivity:
 TBE IgM 51 100 33 35 25 18
 Borrelia IgM 35 69 18
IgG 33 65 15
IgM and IgG 18 35 7

CSF, cerebrospinal fluid; Ig, immunoglobulin; LB, Lyme borreliosis.

*Of the 44 lumbar punctured.

†Of those with pleocytic CSF.