Table 1 Clinical manifestations.
Number (n = 51) | % | LB‐IgG positive | LB‐IgM positive | Systemic features LB | LB‐IgM and systemic LB | ||
---|---|---|---|---|---|---|---|
Meningeal symptoms: | |||||||
Headache or Meningism | 47 | 92 | 30 | 34 | 23 | 17 | |
CSF pleocytosis | 42 | 95* | |||||
Lymphocytic | 26 | 62† | |||||
Polymorphonuclear | 8 | 19† | |||||
mixed | 8 | 19† | |||||
Neurological features: | |||||||
Tremor | 22 | 43 | 15 | 10 | 4 | 4 | |
Nystagmus | 12 | 24 | 8 | 7 | 2 | 2 | |
Muscle weakness | 21 | 41 | 13 | 16 | 11 | 8 | |
Flaccid paresis arms and shoulders | 14 | 28 | 10 | 11 | 6 | 6 | |
Flaccid paresis legs | 8 | 16 | 6 | 7 | 5 | 4 | |
Spastic paresis | 6 | 12 | 3 | 5 | 4 | 3 | |
Bulbar or respiratory dysfunction | 3 | 6 | 2 | 1 | 2 | 1 | |
Facial palsy | 3 | 6 | 1 | 3 | 1 | 1 | |
Oculomotor disturbances | 2 | 4 | 1 | 1 | |||
Distal polyneuropathy | 4 | 8 | 3 | 2 | 2 | 2 | |
Migrating, radicular, limb pains | 21 | 41 | 13 | 16 | 10 | 8 | |
Systemic features: | |||||||
Biphasic fever | 28 | 55 | 23 | 17 | 12 | 8 | |
Early local erythema (>5 cm) | 7 | 14 | 4 | 4 | |||
Erythema chronicum migrans | 1 | 2 | 1 | 1 | |||
Joint involvement | 9 | 18 | 6 | 7 | |||
Arthralgias | 7 | 14 | 4 | 5 | |||
Swelling | 2 | 4 | 2 | 2 | |||
Atrio‐ventricular block | 5 | 10 | 5 | 3 | |||
His Bundle block | 10 | 20 | 5 | 8 | |||
Seropositivity: | |||||||
TBE | IgM | 51 | 100 | 33 | 35 | 25 | 18 |
Borrelia | IgM | 35 | 69 | 18 | |||
IgG | 33 | 65 | 15 | ||||
IgM and IgG | 18 | 35 | 7 |
CSF, cerebrospinal fluid; Ig, immunoglobulin; LB, Lyme borreliosis.
*Of the 44 lumbar punctured.
†Of those with pleocytic CSF.