Table 1 Histopathological grading (1999 v WHO 2000), treatment, and outcome of 20 patients with atypical and anaplastic/malignant meningiomas.
| Tumour No | Age (y)/sex | Tumour grade (1999 review) | Tumour grade (WHO 2000) | Location | Degree of resection (Simpson grade at initial surgery and surgery for recurrent tumour) | Radiotherapy/radiosurgery | Follow up/outcome | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 46 | 49/M | II | I | L fronto‐dorsal falx | Initial surgery: Simpson 2 | 90 mo: no tumour | ||||||
| 2 | 106 | 76/M | II | I | L frontal convexity | Initial surgery: Simpson l | 1 mo: death (unrelated) | ||||||
| 3 | 234 | 48/M | II | I | R frontodorsal convexity | Initial surgery: Simpson 1 | 86 mo: no tumour | ||||||
| 4 | 287 | 74/F | II | I | L postcentral convexity | Initial surgery: Simpson 1 | 79 mo: no tumour | ||||||
| 5 | 320 | 47/F | II | I | L fronto‐dorsal parasagittal | Initial surgery: Simpson 3–4 | 60 mo: stable residual tumour | ||||||
| 6 | 417 | 38/F | II | I | L fronto‐dorsal falx | Initial surgery: Simpson 1 | 73 mo: no tumour | ||||||
| 117 | 22/F | II | I | L fronto‐median convexity | Initial surgery: Simpson 1 (WHO°I) | ||||||||
| 1st rec (34 mo; tumour 117): Simpson 3 | |||||||||||||
| 303 | 23/F | II | II | Superior sagittal sinus | 2nd rec (43 mo; tumour 303 = rec tumour 117): Simpson 1 | ||||||||
| 8 | 174 | 66/F | II | II | L med‐lat sphenoid wing | Initial surgery: Simpson 2 (WHO°I) | |||||||
| 1st rec (71 mo; tumour 174): Simpson 1 | 81 mo: no tumour | ||||||||||||
| 9 | 262 | 69/F | II | II | R fronto‐dorsal falx | Initial surgery: Simpson 2 | |||||||
| surgery for 2nd men (31 mo, WHO°I) | 50 mo: no tumour | ||||||||||||
| 10 | 268 | 54/F | II | II | R cavernous sinus | Initial surgery: Simpson 4 | 5 mo: stable residual tumour | ||||||
| 11 | 314 | 49/F | II | II | L frontal parasagittal | Initial surgery: Simpson 2 | 2 mo: no tumour | ||||||
| 12 | 378 | 60/F | II | II | L fronto‐lat convexity | Initial surgery: Simpson 1 | 74 mo: no tumour | ||||||
| 13 | 391 | 62/M | II | II | L fronto‐parietal convexity | Initial surgery: Simpson 1 | EBR (after 2nd rec) | 26 mo: death (tumour related) | |||||
| 1st rec (6 mo): Simpson 3 (WHO°III) | |||||||||||||
| 2nd rec (8 mo): Simspon 3 (WHO°III) | |||||||||||||
| 3rd rec (17 mo): Simpson 3 (WHO°III) | |||||||||||||
| 4th rec (22 mo): Simpson 3 (WHO°III) | |||||||||||||
| 14 | 409 | 24/F | II | II | L parieto‐occipital falx | Initial surgery: Simpson 1 | 55 mo: no tumour | ||||||
| 15 | 54 | 74/F | III | II | L frontal convexity | Initial surgery: Simpson 1 Simpson 1 | 1 mo: death (unrelated) | ||||||
| 16 | 83/123 | 56/M | III | II | Mult men: L parietal convexity (tumour 83), L fronto‐basal (tumour 123), L frontal parasagittal, L tentorium | Initial surgery: Simpson 2 (“benign”) | |||||||
| 1st rec (106 mo): Simpson 2 (WHO°I) | EBR (after 2nd rec) | 134 mo: death (tumour‐related) | |||||||||||
| 2nd rec (123 mo; tumours 83, 123 etc.): Simpson 3–4 | |||||||||||||
| 17 | 93 | 70/F | III | II | L med sphenoid wing | Initial surgery: Simpson 2 | 0 mo: death (perioperative) | ||||||
| 18 | 280 | 41/F | III | II | L fronto‐dorsal convexity | Initial surgery: Simpson 1 | 78 mo: no tumour | ||||||
| 19 | 212 | 53/F | III | III | R frontal parasagittal | Initial surgery: Simpson 1 (WHO°III) | |||||||
| 1st rec (48 mo; tumour 212): Simpson 1 | EBR (after 1st surgery) | 48 mo: death (perioperative) | |||||||||||
| 20 | 329 | 44/F | III | III | L fronto‐parietal convexity | Initial surgery: Simpson 1 | |||||||
| 1st rec (4 mo): Simpson 3–4 | RS (after 1st surgery) | 7 mo: death (tumour related) |
EBR, external beam radiotherapy; L, left; lat, lateral; med, medial; men, meningiomas; mo, months; mult, multiple; R, right; rec, recurrence; RS, radiosurgery; sx, surgery; y, years.