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. 2005 Nov 25;77(6):767–773. doi: 10.1136/jnnp.2005.077974

Table 3 Regrading of meningiomas would change recommendations for postoperative radiotherapy/radiosurgery.

After complete resection After incomplete resection
WHO grade I → II (n = 56) WHO grade II → III (n = 55) WHO grade I → II (n = 58) WHO grade II → III (n = 56)
No change 47 (83.9%) 20 (36.4%) 28 (48.3%) 22 (39.3%)
No radiotherapy → EBR 2 (3.6%) 20 (36.4%) 10 (17.2%) 16 (28.6%)
No radiotherapy → radiosurgery/conformal radiotherapy 3 (5.4%) 16 (29.1%) 12 (20.7%) 9 (16.1%)
No radiotherapy → radiotherapy 9 (16.1%) 31 (56.4%) 18 (31.0%) 21 (37.5%)
Other changes* 0 5 (9.1%) 6 (10.3%) 16 (28.6%)

The table details how changing the histological grade (for example, by applying a different grading system) would result in significantly different recommendations for postoperative radiation therapy. Numbers exclude centres recommending radiotherapy only for progressive/recurrent disease or specific tumour locations (for example, cavernous sinus).

*Includes recommending EBR instead of conformal radiotherapy/radiosurgery and vice versa, and applying radiotherapy in selected cases v recommending it to all patients.

EBR, external beam radiotherapy; WHO, World Health Organisation.