Table 3 Regrading of meningiomas would change recommendations for postoperative radiotherapy/radiosurgery.
After complete resection | After incomplete resection | |||
---|---|---|---|---|
WHO grade I → II (n = 56) | WHO grade II → III (n = 55) | WHO grade I → II (n = 58) | WHO grade II → III (n = 56) | |
No change | 47 (83.9%) | 20 (36.4%) | 28 (48.3%) | 22 (39.3%) |
No radiotherapy → EBR | 2 (3.6%) | 20 (36.4%) | 10 (17.2%) | 16 (28.6%) |
No radiotherapy → radiosurgery/conformal radiotherapy | 3 (5.4%) | 16 (29.1%) | 12 (20.7%) | 9 (16.1%) |
No radiotherapy → radiotherapy | 9 (16.1%) | 31 (56.4%) | 18 (31.0%) | 21 (37.5%) |
Other changes* | 0 | 5 (9.1%) | 6 (10.3%) | 16 (28.6%) |
The table details how changing the histological grade (for example, by applying a different grading system) would result in significantly different recommendations for postoperative radiation therapy. Numbers exclude centres recommending radiotherapy only for progressive/recurrent disease or specific tumour locations (for example, cavernous sinus).
*Includes recommending EBR instead of conformal radiotherapy/radiosurgery and vice versa, and applying radiotherapy in selected cases v recommending it to all patients.
EBR, external beam radiotherapy; WHO, World Health Organisation.