Table 3 Factors affecting time to first fall in PD, PSP and MSA: independent predictors from Cox multiple regression analysis on early clinical features, age and sex.
PD | HR | 95% CI | p Value | PSP | HR | 95% CI | p Value | MSA | HR | 95% CI | p Value |
---|---|---|---|---|---|---|---|---|---|---|---|
Age of onset | 1.07 | 1.05–1.08 | <0.001 | Age of onset | 1.05 | 1.01–1.09 | 0.007 | Age of onset | 1.04 | 1.02–1.08 | 0.003 |
Symmetrical onset | 1.86 | 1.25–2.77 | 0.002 | Early postural instability | 3.4 | 1.7–6.8 | 0.001 | Early postural instability | 2.08 | 1.07–3.94 | 0.03 |
Early autonomic dysfunction | 2.56 | 1.32–4.98 | 0.005 | ||||||||
Female gender | 1.39 | 1.05–1.83 | 0.021 |