Figure 5.
Activity of Fab 13.4.1–PE38 on influenza virus-infected cells. (A) Detection of HA255–262 peptide/H-2Kk complexes on influenza virus infected-RMA-k cells by Fab 13.4.1. RMA-k cells were infected with various dilutions of influenza virus strain A2/Japan/305/57, and complexes were detected by FACS analysis using recombinant purified Fab 13.4.1 and FITC-labeled goat anti-mouse IgG or Fab. (B and C) Activity of Fab 13.4.1–PE38 on influenza virus-infected RMA-k cells. RMA-k cells were infected with influenza virus strains A2/Japan and PR-8. After infection cells were assayed for cytotoxicity by Fab 13.4.1–PE38.