Table 4 Antiparkinsonian drugs before and after surgery.
Medication | Before surgery | 12 months after surgery |
---|---|---|
Levodopa (n = number of patients) | 6 | 25 |
Dopamine agonist (n = number of patients) (sc apomorphine) | 2 [1] | 23 [0] |
Levodopa+dopamine agonist (n = number of patients) (sc apomorphine) | 89 [26] | 41 [0] |
Apomorphine repeated injections (n = number of patients) | 23 | – |
Unitary dose (mg) (mean±SD) (number of injections/day) | 11±4 [1–7] | – |
Apomorphine continuous infusion (n = number of patients) | 3 | – |
Flow rate/h (mg) (mean±SD) (number of hours/day) | 5±2 [12–24] | – |
No drug (n = number of patients) | 0 | 6 |
Total (n = number of patients) | 97 | 95 |
Levodopa equivalent daily dose (mg) (mean±SD) | 1240±586 | 506±429** |
**p<0.0001 for the comparison with the preoperative dose.