Table 3 Frequency distributions, ORs (95% CIs) and likelihood ratio testing (LRT) of C677T MTHFR genotype×hypertension×smoke×case status.
| Genotype | Patients (n = 174) | Controls (n = 159) | Specific ORs | 95% CI | Conditional ORs | p Value (LRT) | |
|---|---|---|---|---|---|---|---|
| Non‐smoker | |||||||
| Non‐hypertensive | CC or CT | 56 | 96 | 1 | Reference | ||
| TT | 20 | 14 | 2.45 | 1.15 to 5.23 | 2.45 | Reference | |
| Hypertensive | CC or CT | 12 | 4 | 5.14 | 1.58 to 16.7 | ||
| TT | 1 | 1 | 1.71 | 0.11 to 28.0 | 0.33 | 0.224 | |
| Smoker | |||||||
| Non‐hypertensive | CC or CT | 56 | 28 | 3.43 | 1.96 to 6.01 | ||
| TT | 12 | 7 | 2.94 | 1.09 to 7.90 | 0.86 | 0.114 | |
| Hypertensive | CC or CT | 12 | 5 | 4.11 | 1.38 to 12.3 | ||
| TT | 5 | 0 | 18.6 | 1.02 to 347 | 4.54 | 0.039 |
MTHFR, methylenetetrahydrofolate reductase gene.