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. 2006 Feb;77(2):203–207. doi: 10.1136/jnnp.2005.072355

Table 3 Major groups of diseases stratified for sex and time of death, comparison between patients with MG and matched controls.

Age at death Male patients (n = 100) Male controls (n = 500) p Female patients (n = 149) Female controls (n = 745) p
Respiratory tract disease
 1951–1968 4/19 (21.1) 1/36 (2.8) 0.025* 5/36 (13.9) 5/74 (6.8) 0.22
 1969–1985 16/39 (41.0) 39/182 (21.4) 0.010* 13/44 (29.5) 40/193 (20.7) 0.21
 1986–1995 10/23 (43.5) 54/258 (20.9) 0.013* 9/42 (21.4) 84/377 (22.3) 0.90
 1996–2001 5/19 (26.3) 10/24 (41.7) 0.29 8/27 (29.6) 27/101 (26.7) 0.76
 Total 35/100 (35.0) 104/500 (20.8) 0.002* 35/149 (23.5) 156/745 (20.9) 0.49
Cardiac disease
 1951–1968 1/19 (5.3) 13/36 (36.1) 0.013* 2/36 (5.6) 13/74 (17.6) 0.09
 1969–1985 8/39 (20.5) 107/182 (58.8) <0.001* 14/44 (31.8) 81/193 (42.0) 0.22
 1986–1995 13/23 (56.5) 120/258 (46.5) 0.36 15/42 (35.7) 149/377 (39.5) 0.63
 1996–2001 7/19 (36.8) 13/24 (54.2) 0.26 12/27 (44.4) 44/101 (43.6) 0.94
 Total 29/100 (29.0) 253/500 (50.6) <0.001* 43/149 (28.9) 287/745 (38.5) 0.026*
Malignant disease
 1951–1968 0/19 7/36 (19.4) 0.040* 0/36 32/74 (43.2) <0.001*
 1969–1985 2/39 (5.1) 34/182 (18.7) 0.038* 5/44 (11.4) 62/193 (32.1) 0.006*
 1986–1995 5/23 (21.7) 62/258 (46.5) 0.81 0/42 105/377 (27.9) <0.001*
 1996–2001 4/19 (21.1) 8/24 (33.3) 0.37 6/27 (44.4) 29/101 (28.7) 0.50
 Total 11/100 (11.0) 111/500 (22.2) 0.011* 11/149 (7.4) 228/745 (30.6) <0.001*
Cerebrovascular disease
 1951–1968 1/19 (5.3) 2/36 (5.6) 0.96 0/36 6/74 (8.1) 0.08
 1969–1985 5/39 (12.8) 32/182 (17.6) 0.47 5/44 (11.4) 36/193 (18.7) 0.25
 1986–1995 2/23 (8.7) 47/258 (18.2) 0.25 5/42 (11.9) 82/377 (21.8) 0.14
 1996–2001 4/19 (21.1) 2/24 (8.3) 0.23 3/27 (11.1) 20/101 (19.8) 0.30
 Total 12/100 (12.0) 83/500 (16.6) 0.25 13/149 (8.7) 144/745 (19.3) 0.002*

The fraction, as well as the percentage (in brackets), shows the occurrence of the disease compared with all deceased individuals of the same sex who died in the same time period. Pearson χ2 tests were used. *Statistical significance.