Table 1 Prognostic factors according to Cox multivariate analysis.
Increased risk of death | p Value | ||
---|---|---|---|
FVC <80% at diagnosis | No | 1 | 0.0004 |
Yes | 4.11 | ||
PEG | Yes | 1 | 0.0006 |
No | 3.38 | ||
Age groups (years) | ⩽50 | 1 | 0.004 |
51–60 | 1.40 | ||
61–70 | 1.95 | ||
>70 | 2.72 | ||
Attending a tertiary centre for ALS | Yes | 1 | 0.006 |
No | 1.61 | ||
Bulbar onset | No | 1 | 0.009 |
Yes | 1.45 | ||
Riluzole treatment | Yes | 1 | 0.05 |
No | 1.31 |
The other variables that were included, but did not show significant results, were sex, delay in diagnosis and non‐invasive positive‐pressure ventilation. Riluzole treatment, percutaneous endoscopic gastronomy (PEG) and non‐invasive ventilation were included as time‐dependent variables.
ALS, amyotrophic lateral sclerosis; FVC, forced vital capacity.