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. 2006 Sep 29;78(2):147–151. doi: 10.1136/jnnp.2006.100222

Table 3 Characteristics of patients with parkinsonism.

Patient 1 Patient 2 Patient 3 Patient 4 Patient 5 Patient 6 Patient 7 Patient 8 Patient 9
Age (years) 55 49 42 43 44 61 39 29 51
Age at diagnosis of epilepsy (years) 46 27 7 27 Birth 53 5 23 Late teens
Sex F M M M F F F F M
Anticonvulsant drugs at time of assessment Carbamazepine, lamotrigine Lamotrigine Vigabatrin, zonisamide Valproate, clobazam Valproate Valproate, gabapentin Valproate Valproate, carbamazepine Valproate
UPDRS* 10.5 13 11 13 14 15 16 16.5 18
Duration on VPA (years) 2 7 4 2 13 16
Other movement disorders Postural tremor Postural tremor Postural tremor Postural tremor, dystonia Postural tremor Postural tremor
Other features of potential importance Retinitis pigmentosa Taking risperidone for 3 months at the time of assessment Atypical tremor with variability and distractibility Coeliac disease diagnosed 6 months before onset of seizures Cerebral palsy with mild left sided hemiparesis; left limbs smaller than right Neurofibromatosis;
Acute onset, progressive cognitive decline 2 years after starting valproate
Seizure type Complex partial Complex partial Complex partial Simple partial with secondary generalisation Complex partial Unclassified Complex partial Complex partial Primary generalised

F, female; M, male; UPDRS, Unified Parkinson's Disease Rating Scale; VPA, valproate .

*Modified UPDRS III (all items of UPDRS III were assessed, but only the most involved hemibody (upper and lower limbs) was recorded for items 20, 21, 22, 23, 24, 25 and 26 for a total maximum score of 56).