Table 2.
Atherosclerotic lesion areas of immunocompetent and immunodeficient mice
| Diet | Genotype | Gender | Lesion area, μm2 |
|---|---|---|---|
| Chow | E0/R1 | Male (n = 12) | 136,144 ± 27,365 (132,400) |
| Female (n = 9) | 145,117 ± 26,466 (161,100) | ||
| Combined | 139,990 ± 18,879 (139,900) | ||
| E0/R0 | Male (n = 9) | 70,609 ± 7745 (74,120)* | |
| Female (n = 9) | 91,262 ± 14,840 (74,870) | ||
| Combined | 80,936 ± 8,497 (74,490)† | ||
| Western | E0/R1 | Male (n = 4) | 433,767 ± 65,972 (432,200) |
| Female (n = 6) | 545,441 ± 46,603 (520,500) | ||
| Combined | 500,771 ± 40,458 (497,700) | ||
| E0/R0 | Male (n = 7) | 462,361 ± 49,368 (469,400) | |
| Female (n = 6) | 413,229 ± 53,833 (405,300) | ||
| Combined | 439,685 ± 35,545 (448,800) |
Values are expressed as mean lesion area ± SEM. Median lesion areas are in parentheses. ∗, P = 0.047 by Mann–Whitney U test as compared with male E0/R1; †, P = 0.022 by Mann–Whitney U test as compared with combined male and female E0/R1.