Table 2 Additional risk factors for neuropathy in patients with DM and DSP: laboratory evaluation.
| Abnormal laboratory value | n |
|---|---|
| Low serum B1 level (nl: 9–44 nmol/l) | 10 |
| Low serum B6 level (nl: 5–50 μg/l) | 11 |
| Serum immunofixation with | 8 |
| monoclonal protein detected | |
| Elevated methylmalonic acid level | 8 |
| (>0.40 μmol/l) | |
| Elevated homocysteine level (>13 μmol/l) | 7 |
| (and normal methylmalonic acid level) | |
| Hypertriglyceridaemia (>500 mg/dl) | 8 |
| ANA >1:160 | 7 |
| Elevated C‐reactive protein (>1.6 mg/dl) | 7 |
| ESR >60 mm/h | 6 |
| Abnormal renal function studies | 4 |
| (creatinine >2.0 mg/dl) | |
| Elevated ACE level (>60 U/l) | 4 |
| RF >1:160 | 4 |
| Elevated anti‐IgG gliadin antibody (>50 EU) | 3* |
| Elevated anti‐MAG antibody (>1:6400) | 3† |
| Elevated anti‐DNA antibodies (>31 IU) | 2‡ |
| Elevated B6 level (>125 μg/l) | 2 |
| Low serum B12 level (<200 mg/dl) | 2 |
| Elevated anti‐sulfatide antibody (>1:2500) | 2¶ |
| Elevated WBC level (>16×109/l) | 2§ |
| Positive serum ANCA level | 1** |
*One with elevated tissue transglutaminase at 75 EU, none had jejunal biopsy; †2 of 3 with M‐spike; ‡both with normal ANA and no associated diagnosis; ¶1 with IgG M‐spike; §both diagnosed with chronic lymphocytic leukaemia; **no associated diagnosis.
nl, normal value.