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. 2006 Nov 6;78(4):386–390. doi: 10.1136/jnnp.2006.100545

Table 1 Summary of clinical features and disease associations.

Total Children Adults
AChR Ab‐ positive* AChR Ab‐negative* AChR Ab‐positive* AChR Ab‐negative*
Total 127 70 127 64
F:M 76:51 29:41 76:51 34:30
Maximum MGFA grade, n
 1 227 103 54 31 39
 2a 50 11 10 19 10
 2b 53 10 2 30 11
 3a 5 0 1 3 1
 3b 34 3 2 26 3
 4a 4 0 1 3 0
 4b 6 0 0 6 0
 5 9 0 0 9 0
Thymic pathology (MRI), n
 Normal† 98 52 63 48
 Thymitis 26 18 29 12
 Thymoma 3 0 35 4
Hyperthyroidism 16 5 16 17

Ab, antibody; AChR, acetylcholine receptor; F, female; M, male; MGFA, Myasthenia Gravis Foundation of America.

*Most of the AChR antibodies were not measured at the time of maximum disease severity.

†Normal refers to normal for age at the time of MRI; this would include adults with thymic atrophy.