Table 2.

Abnormal behavior ratings

Rating	Abnormal behavior category
1	No abnormal behavior detected. Never referred to Psychological Well- being Program staff for abnormal behavior. Behavioral observations by trained staff support absence of abnormal behavior.
2	Never referred; no other information; no SIB (defined as self-injury sufficient to break the skin) in animal's clinical record.
3	Low levels of abnormal behavior (excluding self-injurious behavior – SIB - or potentially self-injurious behavior); e.g., infrequent locomotor stereotypy, overgrooming, feces smearing, self-clasping. Low levels defined as >0 to <15% of time budget spent engaging in abnormal behavior or observed in ≤25% of behavioral assessment visits. Half of the 58 subjects were rated 3 or below (median split).
4	Minor levels of abnormal behavior (without any self-injurious or potentially self-injurious behavior). Minor levels defined as 15% to <20% of time budget spent engaging in abnormal behavior or observed in >25% to ≤50% of behavioral assessment visits.
5	Minor or low levels of abnormal behavior that include potentially self- injurious behavior (e.g., self-biting or self-hitting that does not break the skin); no SIB in animal's clinical record.
6	Frequent abnormal behavior (primarily frequent locomotor stereotypy such as pacing) but no SIB or potentially self-injurious behavior. Frequent defined as ≥20% of time budget spent engaging in abnormal behavior or observed in >50% of behavioral assessment visits.
7	Frequent abnormal behavior including any level of potentially self-injurious behavior; no SIB in animal's clinical record. Example: animals that self-bite without injury and also engage in frequent locomotor stereotypy.
8-15	Animals with history of injury-producing SIB, ratings ordered by temporal proximity to POMC blood collection: 8, the animal with its last SIB episode most distant in time, to 15, the animal with SIB episodes around the time of POMC blood collection.