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The structure of the Dmp1 (Dmtf1) transcription factor. Both murine and human Dmp1 has three tandem myb-like repeats with two transactivation domains. Mutation of the lysine residue into glutamic acid abolishes its DNA binding. The cyclin Dinteraction domain has been mapped to the amino-terminal segment of the DNA-binding domain. The negative regulatory domain (NR) that is found in c-Myb has not been identified in Dmp1.
