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Elevated levels of heparanase in HD. Plasma samples of pediatric patients with HD were obtained at (■) diagnosis and at (
) restaging following chemotherapy. Heparanase levels were quantified for the (A) entire group (n = 19), (B) patients that were diagnosed to undergo CR (n = 16), and (C) patients that exhibit disease progression. (D) Heparanase levels at (■) diagnosis and (□) restaging are shown for each individual patient.
