Table 4.

Surrogate Markers for Hepatic Fibrosis in HCC Patients, By TNF308.2 Allele Status.

Parameter	TNF308.2 Allele		P
	Present (n = 28)	Absent (n = 80)
Platelet (x 109 l-1)	79 (28–124)	137 (40–390)	.0001
Prothrombin time (international normalized ratio)	1.2 (1.0–1.5)	1.1 (1.0–1.3)	.001
AP index	8 (6–9)	7 (2–8)	.001
APRI	2.8 (0.7–20.6)	1.6 (0.3–21.6)	.004
CDS	8 (5–18)	6 (0–8)	.0001
Thrombocytopenia* (%)	100.0	62.50	.0003
AP index ≥ 6* (%)	100.0	76.25	.010
APRI ≥ 1.5* (%)	82.14	55.00	.003
CDS ≥ 8* (%)	50.00	2.50	.0001

^*Cutoff values for significant fibrosis were adapted from Lackner et al. [33].