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. 2007 Nov 16;3(11):e209. doi: 10.1371/journal.pgen.0030209

Figure 3. POF and HP1 Colocalize within Genes while HP1 Binding Shows an Additional “Promoter Peak”.

Figure 3

(A) POF and HP1 enrichment profiles at the Thd1 Pur-alpha gene pair locus. POF and HP1 binding at the Ank locus (B) and the Crk locus (C). HP1 binding in salivary glands is shown in dark blue, HP1 in S2 cells in light blue, POF in S2 cells in orange, and POF in salivary glands in red. Genes expressed from left to right are represented by rectangles above the horizontal line in each panel and the genes expressed in the opposite direction are shown below the line. Exons are indicated in black and introns in gray. Note the peak of HP1 enrichment (arrowheads) in the region upstream of the transcription start points of Ank and Crk, present in both S2 cells and salivary glands. All enrichment values for all single probes on the fourth chromosome plotted as HP1 enrichment on the y-axis and POF enrichment on the x-axis for S2 cells (D) and salivary glands (E). Probes in the putative promoter region (−500 to +200 bp from the transcription start point) are shown in black.