Table 1.
At baseline | |
---|---|
Age years, median (range) | 59 (43–76) |
Female sex, (%) | 157 (80%) |
Body mass index (kg/m2), median (range) | 25.7 (20.2–40.0) |
Symptomatic knee OA, n (%)a | 71 (39%) |
Kellgren & Lawrence Score 0/1/2/3/4, No. | 59/53/60/10/0 |
Over 2 years | |
Bone marrow edema-like lesions, n (%)b | 128 (70%) |
Grade 0/1/2/3c | 54/56/62/10 |
Cysts, n (%)b | 100 (55%) |
Grade 0/1/2/3c | 82/60/37/3 |
At 2 years | |
WOMAC Pain scores, median (range)d | 13 (0–99) |
WOMAC Stiffness scores, median (range)d | 18 (0–99) |
WOMAC Function scores, median (range)d | 14 (0–98) |
aDefined as pain or stiffness on most days of the month prior to study entry, in combination with osteophytes on radiographs
bDuring 2 years
cMaximal grade per patient
dn = 157