Table 1.
Glycaemic control in people with type 2 diabetes prescribed two or more oral agents concurrently.
| Number of types of oral agents prescribed | n | Pre-therapy HbA1ca Mean % (SD) | Post-therapy HbA1cb Mean % (SD) | Mean difference % Pre-HbA1c – Post-HbA1c (95% CI) | P-value | Number (%) with HbA1c ≥7.5% post-therapy | Number (%) with HbA1c ≥8.5% post-therapy |
|---|---|---|---|---|---|---|---|
| ≥2 | 5064 | 9.07 (1.51) | 8.16 (1.57) | 0.91 (0.86 to 0.95) | <0.001 | 3153 (62.26) | 1712 (33.81) |
| 2 | 4174 | 9.04 (1.51) | 8.04 (1.51) | 1.00 (0.95 to 1.05) | <0.001 | 2468 (59.13) | 1280 (30.67) |
| 3 | 854 | 9.21 (1.49) | 8.73 (1.72) | 0.48 (0.37 to 0.59) | <0.001 | 658 (77.05) | 411 (48.13) |
| 4 | 36 | 9.16 (1.49) | 9.34 (2.18) | −0.19 (−0.79 to 0.42) | 0.54 | 27 (75.00) | 21 (58.33) |
| Pre-2003 | 2713 | 9.22 (1.56) | 8.28 (1.66) | 0.93 (0.87 to 0.99) | <0.001 | 1755 (64.69) | 1023 (37.71) |
| Post-2003 | 2351 | 8.90 (1.43) | 8.02 (1.46) | 0.87 (0.81 to 0.94) | <0.001 | 1398 (59.46) | 689 (29.31) |
a
Pre-therapy HbA1c (haemoglobin A1c) is the last available HbA1c assessment in the 6 months prior to initiation of a patient's last oral agent.
b
Post-therapy HbA1c is the last available HbA1c assessment in the 6 months following initiation of their last oral agent.