FIG. 4.
Effect of IL-12 dose and schedule on P1A cDNA vaccine-induced P1A-specific CTL response. DBA/2 mice were vaccinated with P1A cDNA (as described in Materials and Methods) on days 0 and 14, and IL-12 given i.p. at the indicated doses on day 1 (A), or cDNA was given on days 0, 1, 2, 7, 8, and 9, and IL-12 protein was given on days 1 and 8 (B). A and B represent independent experiments representative of at least two additional studies of the same schedule and doses.