Table 2 Maximum scores for dimensions and items in the questionnaires assessing the likelihood for biases in case–control and cohort studies.
| Questionnaire dimensions* | Design | ||
|---|---|---|---|
| Case–control | Prospective cohort | Retrospective cohort | |
| Selection bias | |||
| Maximum score† | 44 | 40 | 43 |
| Items‡ | 1–12, 15, 16, 33–35 | 1,2, 4–6, 8–13, 25–27 | 1,2,4, 6–12, 25–27 |
| Disease misclassification bias | |||
| Maximum score | 23 | 24 | 31 |
| Items | 12–16, 33, 34, 36 | 7, 13–16, 25, 26, 28 | 5–7, 13–15, 25, 26, 28 |
| Exposure misclassification bias | |||
| Maximum score | 29 | 25 | 32 |
| Items | 17–24, 33, 34, 37 | 17–20, 25, 26, 29 | 6, 7, 16–18, 25, 26, 29 |
| Bias arising from use of surrogate informants | |||
| Maximum score | 21 | NA | NA |
| Items | 25–28, 33, 34, 38 | NA | NA |
| Bias arising from confounding | |||
| Maximum score | 25 | 25 | 33 |
| Items | 29, 30, 33, 34, 39 | 21, 22, 25, 26, 30 | 6, 7, 21, 22, 25, 26, 30 |
NA, not applicable
*Categories of biases assessed through the different items in the questionnaires.
†Maximum score obtained from the sum of scores for items included in each dimension.
‡Items of the questionnaire (Appendices I and II, available at http://ard.bmjjournals.com/supplemental) included in each dimension.