Table 5 Associations with neurological and psychiatric symptoms in past users of sheep dip.

Risk Factor	All past users of sheep dip	⩾3 Neurological symptoms*			⩾4 Neurological symptoms*			Anxiety*			Depression*
	n¶	n	PR (95% CI)†	PR (95% CI)‡	n	PR (95% CI)†	PR (95% CI)‡	n	PR (95% CI)†	PR (95% CI)‡	n	PR (95% CI)†	PR (95% CI)‡
Lifetime use of sheep dip (days)
<10	416	17	1.0	1.0	9	1.0	1.0	90	1.0	1.0	48	1.0	1.0
10–49	700	35	1.3 (0.7 to 2.4)	1.3 (0.7 to 2.4)	17	1.3 (0.6 to 2.8)	1.3 (0.6 to 2.9)	150	1.0 (0.8 to 1.3)	1.0 (0.8 to 1.3)	84	1.1 (0.7 to 1.5)	1.1 (0.8 to 1.5)
50+	693	54	2.1 (1.2 to 3.6)	1.6 (0.9 to 2.8)	28	2.1 (1.0 to 4.6)	1.4 (0.6 to 3.0)	160	1.2 (0.9 to 1.5)	1.0 (0.8 to 1.4)	110	1.4 (1.0 to 2.0)	1.2 (0.9 to 1.8)
Handled sheep dip concentrate
No	544	31	1.0	1.0	14	1.0	1.0	129	1.0	1.0	78	1.0	1.0
Yes	1369	80	1.1 (0.7 to 1.6)	1.0 (0.6 to 1.5)	44	1.3 (0.7 to 2.4)	1.1 (0.6 to 2.1)	295	0.9 (0.7 to 1.1)	0.9 (0.7 to 1.1)	181	0.9 (0.7 to 1.2)	0.9 (0.7 to 1.2)
Ever experienced symptoms within 48 h of work with sheep dip
Never	1355	58	1.0	1.0	26	1.0	1.0	258	1.0	1.0	155	1.0	1.0
Fever or chills§	101	14	3.9 (2.1 to 7.1)	2.1 (1.1 to 3.9)	7	4.9 (2.0 to 11.6)	1.9 (0.8 to 5.0)	33	1.7 (1.2 to 2.5)	1.1 (0.8 to 1.6)	26	2.3 (1.5 to 3.5)	1.5 (1.0 to 2.3)
⩾4 symptoms§	156	31	5.1 (3.2 to 7.9)	2.4 (1.5 to 3.9)	17	6.8 (3.6 to 12.8)	2.7 (1.4 to 5.5)	58	2.0 (1.5 to 2.6)	1.2 (0.9 to 1.6)	47	2.6 (1.9 to 3.7)	1.6 (1.1 to 2.2)

*For each outcome, the comparator for risk estimates was all men who did not have the outcome.

†Adjusted for age (in eight bands) and area.

‡Adjusted for age, area and somatising tendency (classified as in table 4).

§These risk factors overlapped. Each was analysed separately relative to never having experienced acute symptoms.

¶Information on risk factors was missing for some subjects.