Table 3.
Day 11
|
Day 28
|
Day 98
|
||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
CD3 | CD4 | CD8 | Cl II | CD3 | CD4 | CD8 | Cl II | CD3 | CD4 | CD8 | Cl II | |
comb | 0.3 (0.3) | 0.1 (0.1) | 0 (0) | 0.4 (0.1) | 0 (0) | 0 (0) | 0.1 (0.1) | 0.1 (0.1) | 1.2 (0.6) | 0.3 (0.3) | 0.1 (0.1) | 0 (0) |
L6 | 2.8 (0.4) | 2.0 (0.4) | 3.0 (0) | 2.8 (0.2) | 2.2 (0.6) | 1.4 (0) | 2.4 (0.3) | 1.3 (0.4) | 1.2 (0.4) | 0.3 (0.2) | 0.9 (0.4) | 0.4 (0.6) |
Immunohistochemical staining for CD3+, CD4+, CD8+, MHC class II was performed on the same mice described in Fig. 3. Naive animals were analyzed at the same time. The sections were scored using a 0–4 scale (20) to grade portal inflammation. The mean values are given within each experimental group (n = 3) and the standard deviations are given in parentheses.