Table 3.
Literature data
| Authors | Number of patients | Parameter | Dose per fraction/total dose | Time of data collection | Results (%, Pannewitz class.) | |||
| +++ | ++ | + | 0 | |||||
| Fuchs u. Hofbauer (1957)11 | 28 | Pain Mobility | 60 – 100 R/600 – 1500 R | End of RT | 79% | 17% | -- | 4% |
| Braun u. Jakob (1965)12 | 25 | Pain Mobility | 100 – 140 R/300 – 1640 R | Not stated | 64% | 32% | -- | 4% |
| Schertel (1968)13 | 89 | Pain Mobility | 100 R/400 – 600 R | 6 weeks after RT | 2% | 18% | 43% | 49% |
| Wieser (1969)14 | 160 | Pain | 40 – 120 R/500 R | End of RT | 22% | 45% | 22% | 11% |
| Keinert (1972)15 | 145 | Pain Mobility | 30 – 100 R/400 R | Several weeks after RT | 50% | 41% | -- | 9% |
| Zilberberg et al. (1976)16 | 200 | Pain Mobility | 120 R/1200 R | 4 weeks after RT | 46% | 24% | 16% | 14% |
| Hassenstein (1979)17 | 233 | Pain Mobility | 0.5 – 1 Gy/1.5 – 3 Gy | 4–6 weeks after RT | 43% | 31% | -- | 26% |
| Goerlitz (1981)18 | 50 | Pain Mobility | 0.5 Gy/4 Gy | 3 months after RT | 48% | 34% | -- | 18% |
| Hess (1988)19 | 164 | Pain | 0.3 – 0.5 Gy/up to 3 Gy | Several time intervals | 49% | 27% | -- | 24% |
| Sautter-Bihl (1993)20 | 30 | Pain Mobility | 0.5 – 1 Gy/2.5 – 6 Gy | End of RT | 33% | 27% | 27% | 13% |
| Keilholz et al. (1995)21 | 106 | Orthopedic scores | 0.5 Gy/3 Gy | 6 weeks after RT | 49% | 32% | -- | 19% |
| Schaefer u. Micke (1996)22 | 42 | Pain Mobility | 0.5 – 1 Gy/2 – 4 Gy | 6 weeks after RT | 61% | 15% | -- | 24% |
| Heyd (1998)23 | 41 | Pain Mobility | 1 Gy/4 Gy | Several time intervals | 44% | 27% | 17% | 12% |
| Seegenschmiedt (1998)24 | 89 | Pain Orthop. Scores | 0.5/6 Gy (2 × 3 Gy) | 6 weeks after RT | 49% | 26% | 6% | 19% |
| Zwicker et al. (1998)25 | 77 | Pain Mobility | 1 Gy/6 Gy | 3 months after RT | 34% | 35% | 20% | 11% |
| Schultze (2004)26 | 94 | Pain Mobility | 0.75 Gy/6 Gy | 4 months after RT | 18% | 27% | 14% | 41% |
| Own results | 141 | Pain Mobility | 1.0 Gy/6 Gy | 4.5 months after RT | 19% 13% | 39% 45% | 11% 11% | 31% 30% |
Comparison of literature data with our results
Explanation of abbreviations:
+++: painless
++: markedly improved
+: improved
0: stable or worse