Table 1.
Fetal arterial blood gases, pH, oxygen content and lactate levels in control (A) and pre-hypoxic (B) fetuses during the period of repeated complete cord occlusion and 24 (Day +1) and 72 h (Day +2) after the last occlusion.
| A | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Pre | Occ I | Pre | Occ II | Pre | Occ III | Pre | Occ IV | Day +1 | Day +3 | |
| PH | 7.35±0.01 | 7.11±0.04 | 7.26±0.01 | 7.03±0.03 | 7.23±0.01 | 7.02±0.04 | 7.21±0.02 | 7.05±0.05 | 7.35±0.01 | 7.34±0.01 |
| PCO2 mmHg | 55±1 | 90±8 | 55±1 | 98±6 | 55±1 | 94±6 | 55±1 | 86±8 | 55±1 | 55±1 |
| PO2 mmHg | 22±2 | 7±2 | 21±1 | 7±1 | 22±2 | 7±1 | 23±2 | 8±2 | 20±1 | 19±1 |
| SatHb % | 53±4 | 16±7 | 51±3 | 10±1 | 52±3 | 11±2 | 51±4 | 15±4 | 50±3 | 49±3 |
| O2 ct mL/dL | 7.7±1 | 2.6±1 | 7.4±0.7 | 2.9±1.1 | 7.6±0.8 | 2.9±1 | 7.4±0.8 | 2.5±0.9 | 6.9±1 | 7.4±0.8 |
| BD mEq/L | −3.3±0.6 | 5.7±1 | 3.8±0.7 | 10.2±1.4 | 4.8±0.4 | 11.3±0.9 | 6.5±1 | 11±1.7 | −3.3±0.2 | −2±0.4 |
| [Lactate] mM | 1.4±0.2 | 3.7±0.7 | nd | 4.8±1 | nd | 5±1 | nd | 5.1±1 | 2.1±0.5 | 2±0.4 |
|
| ||||||||||
| B | ||||||||||
| PH | 7.36±0.00 | 7.07±0.05 | 7.27±0.02 | 6.97±0.02* | 7.22±0.01 | 6.96±0.02* | 7.19±0.01 | 6.95±0.02* | 7.36±0.01 | 7.35±0.01 |
| PCO2 mmHg | 53±2 | 98±8 | 55±3 | 105±4 | 54±3 | 97±3 | 54±3 | 94±4 | 53±1 | 52±1 |
| PO2 mmHg | 14±1* | 5±1 | 16±1* | 5±1 | 17±1* | 6±1 | 17±1* | 5±1 | 16±1* | 15±1* |
| SatHb % | 34±3* | 11±2 | 33±5* | 9±1 | 34±5* | 10±1 | 36±4* | 10±1 | 40±3* | 37±2* |
| O2 ct mL/dL | 5.1±0.3* | 1.7±0.4 | 5±0.6* | 3.5±1.8 | 4.6±0.6* | 1.5±0.1 | 5.4±0.6* | 1.6±0.1 | 5.1±0.5* | 5.7±0.5* |
| BD mEq/L | −2.4±0.4 | 7.2±1.8 | 2.8±1.1 | 13.8±1.1 | 7.2±0.5 | 16.2±0.3* | 9±0.5 | 16.8±0.7* | −2.7±0.7 | −2±0.5 |
| [Lactate] mM | 1.7±0.2 | 3.7±0.5 | nd | 4.9±0.7 | nd | 6.3±0.5 | nd | 5.5±0.5 | 1.7±0.4 | 1.7±0.4 |
*
p<0.05 when compared to control group; nd: not measured.