Table 4.
Telomere length in cloned mammals
| Reference | Species | Donor cells | Number of cloned animals | Telomere length in clonesa | Telomere activity in clones |
|---|---|---|---|---|---|
| Shiels et al., 1999 | Sheep | Mammary epithelial cells | 3 | D=C<A | Not tested |
| Wakayama et al., 2000 | Mouse | Cumulus cells | 35 | D<C | Not tested |
| Tian et al., 2000 | Bovine | Adult fibroblasts and cumulus cells | 10 | D<C=A | Detected |
| Kato et al., 1998 | Bovine | Adult ear cells | 3 | Ear cells: D<C | |
| White blood cells: D>C=A | |||||
| Lanza et al., 2000 | Bovine | Senescent fibroblasts | 6 | D<C>A | Detected |
| Betts et al., 2001 | Bovine | Adult fibroblasts | Total 21 | D<C=A | Detected |
| Fetal fibroblasts | |||||
| Granulosa cells | |||||
| Miyashita et al., 2002 | Bovine | Oviductal epithelial cells | 9 | D>C<A | Not tested |
| Mammary epithelial cells | 1 | D>C<A | Not tested | ||
| Muscle cells | 2 | D=C<A | Not tested | ||
| Skin fibroblasts | 2 | D=C<A | Not tested | ||
| Blastomere cells | 6 | C>A | Not tested | ||
| Clark et al., 2003 | Sheep | Fetal fibroblasts | 2 | D<C<A | Not tested |
a
A: age-matched control animals derived from fertilization, C: cloned animals and D: donor animals.