Table 2.
Factors associated with adherence to antihypertensive drugs (n=200). Values are mean (95% confidence interval) percentage of days on which correct dose of drugs was taken
| Variables | Primary outcome: correct dosing* | ||
|---|---|---|---|
| Univariate | Multivariable model 1† | Multivariable model 2‡ | |
| Special care§: | (P=0.048) | (P=0.016) | (P=0.030) |
| Yes | 48.1 (35.8 to 60.4) | 42.3 (30.6 to 53.9) | 42.8 (30.8 to 54.7) |
| No | 32.4 (22.6 to 42.3) | 25.6 (15.2 to 36.0) | 27.9 (19.7 to 47.9) |
| Education status: | (P=0.001) | (P<0.001) | (P=0.001) |
| Illiterate | 41.4 (35.1 to 47.6) | 33.7 (27.9 to 39.6) | 35.5 (29.6 to 41.4) |
| Primary school | 35.2 (29.5 to 40.9) | 26.8 (21.5 to 32.1) | 29.8 (24.0 to 35.6) |
| Secondary school | 41.5 (35.4 to 47.5) | 27.6 (21.2 to 34.0) | 29.2 (22.8 to 35.6) |
| Graduate and above | 56.7 (47.0 to 66.4) | 47.6 (39.1 to 56.0) | 46.9 (38.6 to 55.2) |
| Encouraged by family: | (P<0.001) | (P<0.001) | (P<0.001) |
| Yes | 44.5 (40.9 to 48.1) | 41.1 (36.6 to 45.6) | 42.1 (37.6 to 46.6) |
| No | 26.7 (20.2 to 33.1) | 26.7 (20.6 to 32.9) | 28.6 (22.4 to 34.8) |
| Belief in taking drugs to treat illness: | (P<0.001) | (P<0.001) | (P<0.001) |
| Yes | 44.5 (41.0 to 48.0) | 43.6 (39.4 to 47.7) | 44.9 (40.7 to 49.2) |
| No | 21.5 (13.3 to 29.8) | 24.3 (17.0 to 31.5) | 25.8 (18.6 to 33.0) |
| Explaining purpose of drug(s) to patient: | (P<0.001) | (P=0.023) | |
| Yes | 50.1 (43.9 to 56.3) | – | 31.7 (27.2 to 36.2) |
| No | 36.7 (33.0 to 40.4) | – | 34.7 (29.6 to 39.8) |
*Defined as percentage of prescribed doses taken during monitored interval.
†Includes patient related factors.
‡Includes patient related and training related factors.
§Care given by general practitioners intensively trained in management of hypertension.
P value for special care is based on MS(cluster) as error term; P values for all other variables are based on MS(error).