Table 1.
WT
|
TAC
|
RAS
|
||||
---|---|---|---|---|---|---|
Mean ± SEM | n | Mean ± SEM | n | Mean ± SEM | n | |
LVEDD, mm | 3.9 ± 0.1 | 31 | 3.9 ± 0.2 | 5 | 3.9 ± 0.2 | 12 |
LVESD, mm | 2.3 ± 0.1 | 31 | 2.1 ± 0.2 | 5 | 2.4 ± 0.2 | 12 |
FS, % | 41.2 ± 0.1 | 31 | 47.1 ± 2.3 | 5 | 39.0 ± 2.0† | 12 |
IVS, mm | 0.7 ± 0.0 | 30 | 0.9 ± 0.0 | 5 | 0.9 ± 0.1* | 12 |
PW, mm | 0.7 ± 0.0 | 31 | 0.8 ± 0.1 | 5 | 1.2 ± 0.1*† | 12 |
HR, beats/min | 368 ± 24 | 6 | 309 ± 43 | 4 | 397 ± 19 | 9 |
LVESP, mmHg | 106.7 ± 4.4 | 6 | 101.1 ± 10.0 | 4 | 109.8 ± 9.0 | 9 |
LVEDP, mmHg | 2.3 ± 0.4 | 6 | 5.2 ± 1.5 | 4 | 5.6 ± 1.1 | 9 |
Max dP/dt, mmHg/s | 8979 ± 737 | 6 | 6328 ± 460 | 4 | 8411 ± 695 | 9 |
Min dP/dt, mmHg/s | −7,058 ± 308 | 6 | −5,416 ± 179 | 4 | −6,756 ± 479 | 9 |
LVEDD, LV end-diastolic dimension; LVESD, LV end-systolic dimension; FS, fractional shortening; IVS, interventricular septal thickness; PW, LV posterior wall thickness; HR, heart rate; LVESP, LV end-systolic pressure; LVEDP, LV end-diastolic pressure; dP/dt, instantaneous rate of change of pressure with respect to time.
P < 0.05 vs. WT;
P < 0.05 vs. TAC.