Table 1.

Expression rate versus cell survival over time of ABCs expressing full-length versus N-terminal htau constructs

Days p.i.	Three-repeat full-length htau		N-terminal htau fragment
	Expression	Cell survival	Expression	Cell survival
2–6	4/54 (7.4)	54/82 (66)	2/20 (10)	20/35 (62.5)
7–15	16/75 (21.3)	75/150 (50)	9/45 (20)	45/80 (56.5)
16–38	16/31 (51.6)	31/65 (47)	8/44 (18.2)	44/75 (58.6)

Expression and cell survival rates are compared between ABCs expressing full-length (three-MT binding repeat, no GFP tag) and N-terminal constructs of htau. Only sections stained with TAU-1 after AP treatment were scored for expression. ABCs expressing htau or surviving injection (numerators) are given as a fraction of the total number of surviving ABCs at the time of fixation or the total number of injected cells, respectively (denominators). Figures in parentheses give these data as percentages. The increase in the percentage of ABCs expressing full-length tau between each timepoint was significant (P < 0.005, χ² test), whereas no significant change was seen with time in the proportion of ABCs expressing N-terminal fragments. The decrease in survival rate between the first and last timepoints was also significant for full-length but not N-terminal constructs (P < 0.05, χ² test).