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Neuronal toxicity induced by human (Upper) and rat (Lower) amylin. Rat primary hippocampal neurons were treated for 6 days with different concentrations of amylins. Human amylin induced concentration-dependent marked losses in MTT values down to 38% of controls. Rat amylin did not induce significant changes in MTT values at the concentrations used. ∗, P < 0.01 as control treatments.
