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. 1991 Jun;173(12):3930–3932. doi: 10.1128/jb.173.12.3930-3932.1991

The tyrosine repressor negatively regulates aroH expression in Escherichia coli.

G K Muday 1, D I Johnson 1, R L Somerville 1, K M Herrmann 1
PMCID: PMC208031  PMID: 1675635

Abstract

The levels of the tryptophan-sensitive isoenzyme of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase of Escherichia coli, encoded by the aroH gene, were elevated in tyrR and/or trpR mutants. The effect of tyrR and trpR lesions on aroH expression was confirmed by using a lacZ reporter system. The mutational elimination of either repressor led to a threefold increase in beta-galactosidase.

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Selected References

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