Table 7.

Glasgow Coma Score (GCS), Acute Physiology and Chronic Health Evaluation score (APACHE II), and Sepsis-related Organ Failure Assessment (SOFA) score with respect to clinical presentation of sepsis

	Score (median, range)*
Scale	sepsis (n=100)	severe sepsis (n=89)	septic shock (n=86)	multiple organ dysfunction syndrome (MODS) (n=39)	multiple comparisons	P†
Day 1:
GCS	14 (3-15)	13 (3-15)	9 (3-15)	11 (3-15)	sepsis/septic shock	<0.001
					sepsis/MODS	<0.001
					severe sepsis/septic shock	0.001
APACHE II	15.5 (0-37)	20 (3-34)	24 (0-38)	26 (4-43)	sepsis/severe sepsis	0.001
					sepsis/septic shock	<0.001
					sepsis/MODS	<0.001
					severe sepsis/septic shock	<0.001
					severe sepsis/MODS	0.003
SOFA	4 (0-13)	5 (0-12)	7 (0-15)	9 (1-14)	sepsis/severe sepsis	0.001
					sepsis/septic shock	<0.001
					sepsis/MODS	<0.001
					severe sepsis/septic shock	<0.001
					severe sepsis/MODS	<0.001
					septic shock/MODS	0.003
Day 3:	(n=90)	(n=75)	(n=51)	(n=27)
APACHE II	11 (2-27)	15 (1-32)	21 (9-32)	18 (8-33)
SOFA	2 (0-9)	4 (0-15)	7 (1-15)	9 (1-14)	sepsis/MODS	0.002

*Kruskal-Wallis test, P<0.001 for all.

†post hoc Bonferroni correction for Mann-Whitney test (P<0.008).