Table 1.
Observed frequency of genotypes at CCR5 locus in Lopar and Komiža villages and differences in allele frequencies of del32 mutation between Lopar, Komiža, and general Croatian population*
| Setting | |||
|---|---|---|---|
| Parameter | Lopar | Komiža | Croatia |
| Sample (No. subjects) | 98 | 100 | 303 |
| Number (%) of observed genotypes: | |||
| CCR5WT/WT | 87 (88.7%) | 97 (97.0%) | 263 (86.8%) |
| CCR5WT/del32 | 10 (10.2%) | 3 (3.0%) | 37 (12.2%) |
| CCR5del32/del32 | 1 (1.1%) | 0 (0.0%) | 3 (1%) |
| CCR5 del32 allele frequency | 6.0% | 1.5% | 7.1% |
| P | 0.651† | 0.014‡ | 0.037§ |
*Data on general Croatian population from ref. 21.
†Lopar vs Croatian general population.
‡Komiža vs Croatian general population.
§Lopar vs Komiža.