Figure 6.

Relationship of conduction velocity (CV) and action potential (AP) duration for sensory neurons recorded by intracellular microelectrode, in control neurons and fifth lumbar (L5) neurons after spinal nerve ligation (SNL). (A) Control neurons show an inverse relation between CV and AP duration. (B) After injury, there is general prolongation of AP duration, but also the appearance of a new population with very prolonged AP despite a CV characteristic of nociceptive C-type fibers that have CV less than 1.5m/s (vertical line). The horizontal line indicates AP duration of 2 ms. From Sapunar et al (59), with permission.