Table 3.
Diagnostic accuracy (95% confidence interval), sensitivity, specificity and positive (PPV) and negative (NPV) predictive values of clinical signs, white blood cell (WBC) count, C-reactive protein (CRP), interleukin-6 (IL-6) and ultrasonography in diagnosing acute appendicitis
| Indices of diagnostic values |
|||||
|---|---|---|---|---|---|
| Diagnostic method | diagnostic accuracy (median, 95% confidence intervals) | sensitivity (%) | specificity (%) | PPV (%) | NPV (%) |
| Clinical signs* | 69.5 (59.5-79.0) | 93.9 | 33.3 | 52.9 | 87.2 |
| WBC† | 68.4 (57.2-78.3) | 73.5 | 65.6 | 63.1 | 75.6 |
| CRP† | 63.7 (52.1-74.3) | 73.9 | 54.5 | 56.5 | 72.4 |
| IL-6† | 77.6 (67.1-86.1) | 73.5 | 69.7 | 65.9 | 76.7 |
| Ultrasonography* | 92.9 (84.5-98.0) | 91.4 | 95.2 | 93.8 | 93.3 |
*Bayes'’ theorem.
†Receiver-operating characteristic (ROC) curve analysis.